Hydroxytyrosol decreases the oxidative and nitrosative stress levels and promotes angiogenesis through HIF-1 independent mechanisms in renal hypoxic cells /2016/ Martínez-Lara E, Peña A, Calahorra J, Cañuelo A, Siles E. Food Funct. 2016;7(1):540-548. https://doi.org/10.1039/c5fo00928f
Extra Virgin Olive oil improves oxidative stress, functional capacity, and health-related psychological status in patients with fibromyalgia: A Preliminary Study /2017/ Rus A, Molina F, Ramos MM, Martínez-Ramírez MJ, del Moral ML. Biol Res Nurs. 2017 Jan;19(1):106-115. doi: 10.1177/1099800416659370. ISSN: 1099-8004. Q2.
Hypoxia modulates the antioxidant effect of hydroxytyrosol in MCF-7 breast cancer cells /2018/ Calahorra J, Martínez-Lara E, De Dios C, Siles E. PLoS One. 2018;13(9):e0203892. https://doi.org/10.1371/journal.pone.0203892
Insight into the biological pathways underlying fibromyalgia by a proteomic approach /2018/ Ramírez-Tejero JA, Martínez-Lara E, Rus A, Camacho MV, del Moral ML, Siles E. J Proteomics. 2018;186:47-55. https://doi.org/10.1016/j.jprot.2018.07.009
Tyrosol, a simple phenol from EVOO, targets multiple pathogenic mechanisms of neurodegeneration in a C. elegans model of Parkinson’s disease /2019/ García-Moreno JC, Porta de la Riva M, Martínez-Lara E, Siles E, Cañuelo A. Neurobiol Aging. 2019;82:60-68. https://doi.org/10.1016/j.neurobiolaging.2019.07.003
Hydroxytyrosol, the Major Phenolic Compound of Olive Oil, as an Acute Therapeutic Strategy after Ischemic Stroke /2019/ Calahorra J, Shenk J, Wielenga VH, Verweij V, Geenen B, Dederen PJ, Peinado MÁ, Siles E, Wiesmann M, Kiliaan AJ. Nutrients. 2019;11(10):2430. https://doi.org/10.3390/nu11102430
Crosstalk between hydroxytyrosol, a major olive oil phenol, and HIF-1 in MCF-7 breast cancer cells |2020| Calahorra J, Martínez-Lara E, Granadino-Roldán JM, Martí JM, Cañuelo A, Blanco S, Oliver FJ, Siles E. Sci Rep. 2020;10:6361. https://doi.org/10.1038/s41598-020-63417-6
Hydroxytyrosol as a Promising Ally in the Treatment of Fibromyalgia |2020| Ramírez-Tejero JA, Martínez-Lara E, Peinado MÁ, del Moral ML, Siles E. Nutrients. 2020;12:2386. https://doi.org/10.3390/nu12082386
Effect of Uvaol in Human Hepatocarcinoma HepG2 Cells by Affecting G0/G1 Cell Cycle Arrest, ROS Production and AKT/PI3K Signaling Pathway |2020| Bonel-Pérez GC, Pérez-Jiménez A, Gris-Cárdenas I, Parra-Pérez AM, Lupiáñez JA, Reyes-Zurita FJ, Siles E, Csuk R, Peragón J, Rufino-Palomares EE. Molecules. 2020;25:E4254. https://doi.org/10.3390/molecules25184254
Effects of olive oil consumption on cardiovascular risk factors in patients with Fibromyalgia |2020| Rus A, Molina F, Martínez-Ramírez MJ, Aguilar-Ferrándiz MA, Carmona R, del Moral ML. Nutrients. 2020;12(4):918. https://doi.org/10.3390/nu12040918
